Publications

  1. Olsen JM, Åslund A, Bokhari MH, Hutchinson DS, Bengtsson T. Acute β-adrenoceptor mediated glucose clearance in brown adipose tissue; a distinct pathway independent of functional insulin signaling. Mol Metab. 2019 Dec;30:240-249. doi: 10.1016/j.molmet.2019.10.004. Epub 2019 Oct 18. PubMed PMID: 31767175; PubMed Central PMCID: PMC6838983.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838983/
  2. Chia LY, Evans BA, Mukaida S, Bengtsson T, Hutchinson DS, Sato M. Adrenoceptor regulation of the mechanistic target of rapamycin in muscle and adipose tissue. Br J Pharmacol. 2019 Jul;176(14):2433-2448. doi: 10.1111/bph.14616. Epub 2019 Apr 7. Review. PubMed PMID: 30740664; PubMed Central PMCID: PMC6592864.
    https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.14616
  3. Olsen JM, Sato M, Dallner OS, Sandström AL, Pisani DF, Chambard JC, Amri EZ, Hutchinson DS, Bengtsson T. Glucose uptake in brown fat cells is dependent on mTOR complex 2-promoted GLUT1 translocation. J Cell Biol. 2014 Nov 10;207(3):365-74. doi: 10.1083/jcb.201403080. PubMed PMID: 25385184; PubMed Central PMCID: PMC4226734.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226734/
  4. Dehvari N, Hutchinson DS, Nevzorova J, Dallner OS, Sato M, Kocan M, Merlin J, Evans BA, Summers RJ, Bengtsson T. β(2)-Adrenoceptors increase translocation of GLUT4 via GPCR kinase sites in the receptor C-terminal tail. Br J Pharmacol. 2012 Mar;165(5):1442-56. doi: 10.1111/j.1476-5381.2011.01647.x. PubMed PMID: 21883150; PubMed Central PMCID: PMC3372728.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372728/
  5. Sato M, Dehvari N, Oberg AI, Dallner OS, Sandström AL, Olsen JM, Csikasz RI, Summers RJ, Hutchinson DS, Bengtsson T. Improving type 2 diabetes through a distinct adrenergic signaling pathway involving mTORC2 that mediates glucose uptake in skeletal muscle. Diabetes. 2014 Dec;63(12):4115-29. doi: 10.2337/db13-1860. Epub 2014 Jul 9. PubMed PMID: 25008179.
    https://diabetes.diabetesjournals.org/content/63/12/4115
  6. Olsen JM, Csikasz RI, Dehvari N, Lu L, Sandström A, Öberg AI, Nedergaard J, Stone-Elander S, Bengtsson T. β(3)-Adrenergically induced glucose uptake in brown adipose tissue is independent of UCP1 presence or activity: Mediation through the mTOR pathway. Mol Metab. 2017 Mar 30;6(6):611-619. doi: 10.1016/j.molmet.2017.02.006. eCollection 2017 Jun. PubMed PMID: 28580291; PubMed Central PMCID: PMC5444022.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444022/
  7. Dehvari N, da Silva Junior ED, Bengtsson T, Hutchinson DS. Mirabegron: potential off target effects and uses beyond the bladder. Br J Pharmacol. 2018 Nov;175(21):4072-4082. doi: 10.1111/bph.14121. Epub 2018 Jan 18. Review. PubMed PMID: 29243229; PubMed Central PMCID: PMC6177610.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177610/
  8. Mukaida S, Sato M, Öberg AI, Dehvari N, Olsen JM, Kocan M, Halls ML, Merlin J, Sandström AL, Csikasz RI, Evans BA, Summers RJ, Hutchinson DS, Bengtsson T. BRL37344 stimulates GLUT4 translocation and glucose uptake in skeletal muscle via β(2)-adrenoceptors without causing classical receptor desensitization. Am J Physiol Regul Integr Comp Physiol. 2019 May 1;316(5):R666-R677. doi: 10.1152/ajpregu.00285.2018. Epub 2019 Mar 20. PubMed PMID: 30892909.
    https://journals.physiology.org/doi/full/10.1152/ajpregu.00285.2018?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
    or
    https://pubmed.ncbi.nlm.nih.gov/30892909-brl37344-stimulates-glut4-translocation-and-glucose-uptake-in-skeletal-muscle-via-2-adrenoceptors-without-causing-classical-receptor-desensitization/?from_term=BRL37344&from_pos=1